abstract：AIM:To report our data concerning the changes in post-stress and at-rest left ventricular ejection fraction and ventricular volumes in patients with thallium gated SPECT. METHODS:Post-stress and at-rest thallium gated SPECT was performed in 629 consecutive patients; left ventricular ejection fraction (LVEF), left vent...

journal_title：Nuclear medicine communications

authors： del Val Gómez M,Gallardo FG,San Martín MA,Garcia A,Terol I

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Paediatric dual X-ray absorptiometry (DXA) studies present a number of technical problems. One of these is that the edge detection algorithms designed for the adult skeleton may fail for paediatric studies. Hologic provide alternative algorithms for low bone density studies. AIM:To assess low-density softwa...

journal_title：Nuclear medicine communications

authors： Simpson DE,Dontu VS,Stephens SE,Archbold LJ,Lowe V,O'Doherty MJ,Martin N,Coakley AJ

更新日期：2005-06-01 00:00:00

abstract：:We report the use of broth simulation as a means of validating the practice of sub-dispensing from stock vials of long-lived sterile radiopharmaceuticals. 'Matched' vials of nutrient broth accompanied the stock vials of long-lived sterile radiopharmaceuticals during their time in use and were subject to the same handl...

journal_title：Nuclear medicine communications

authors： Murray T,Elliott AT,Hilditch TE

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:90Y is one of the radioisotopes used extensively for therapy due to its favourable nuclear characteristics. Particles and colloids incorporating 90Y are being used for radiation synovectomy, especially in European countries. METHODS:In our present work, 90Y phosphate particles were prepared and evaluated fo...

journal_title：Nuclear medicine communications

authors： Pandey U,Bapat KN,Samuel G,Sarma HD,Chaudhari PR,Dhami PS,Kannan R,Venkatesh M

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:18F-Fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) is a very useful imaging technique and is the best modality for the evaluation of many kinds of tumour. However, in the evaluation of hepatocellular carcinoma (HCC), the diagnostic accuracy of routine 60 min static imaging is not satisfactory....

journal_title：Nuclear medicine communications

authors： Lin WY,Tsai SC,Hung GU

更新日期：2005-04-01 00:00:00

abstract：:Single photon emission computed tomography (SPECT) and positron emission tomography (PET) have advanced our understanding of the biological underpinnings of depression. There is, however, considerable variability in the literature. Depression is a complex disorder with marked heterogeneity in diagnosis and treatment. ...

journal_title：Nuclear medicine communications

authors： Smith DJ,Cavanagh JT

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Large-scale clinical trials have demonstrated that beta blocker therapy improves the prognosis of dilated cardiomyopathy (DCM), but cardiac events sometimes occur even in patients showing favourable response to the therapy. In this study, the usefulness of meta-iodobenzyguanidine (MIBG) in predicting cardiac ...

journal_title：Nuclear medicine communications

authors： Fujimoto S,Inoue A,Hisatake S,Yamashina S,Yamashina H,Nakano H,Yamazaki J

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:The recent development of mixed ligand complexes using a 99mTc tricarbonyl synthon has prompted us to revisit the first generation product, 99mTc-t-butyl isonitrile (TBI), for possible myocardial imaging after modification of the 99mTc core to a mixed ligand core of carbonyl and t-butyl isonitrile. The easy a...

journal_title：Nuclear medicine communications

authors： Kothari KK,Satpati D,Joshi S,Venkatesh M,Ramamoorthy N,Pillai MR

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Screening for radioactive material at borders may become more widely introduced in order to prevent illegal transport. All the alarms at Vienna airport so far have been due to recent applications of radionuclides for medical reasons. METHODS:We report a patient who unexpectedly experienced this problem afte...

journal_title：Nuclear medicine communications

authors： Sinzinger H,Aiginger P,Neumann I,Havlik E

更新日期：2005-01-01 00:00:00

abstract：AIM:The purpose of this case-control study was to determine whether semi-quantitative indices derived from salivary time-activity curves (TACs) are useful in the diagnosis and management of xerostomia. METHODS:Twenty-six healthy volunteers and 83 consecutive patients with xerostomia, including a subset of 40 patients ...

journal_title：Nuclear medicine communications

authors： Booker J,Howarth D,Taylor L,Voutnis D,Sutherland D

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The most recent DNA analogues to become commercially available are known as locked nucleic acids (LNAs). The aim of this study was to evaluate the properties of LNAs for antisense targeting. METHODS:A 15 mer LNA antisense to RIalpha mRNA was studied in cell culture. The antisense LNA (5'-amine...

journal_title：Nuclear medicine communications

authors： Zhang Y,He J,Liu G,Venderheyden JL,Gupta S,Rusckowski M,Hnatowich DJ

更新日期：2004-11-01 00:00:00

abstract：AIM:The aim of this study was to design a general nuclear medicine method for fast, accurate and direct determination of the clearance of a radioactive indicator provided that all uptake compartments of the radioactive indicator could be included in the field of view of the gamma camera. METHODS:The data material for ...

journal_title：Nuclear medicine communications

authors： Carlsen O

更新日期：2004-10-01 00:00:00

abstract：:Uterine leiomyomas, benign tumours of the human uterus, are the most common uterine neoplasm and are composed of smooth muscle with varying amounts of fibrous connective tissue. As a functional imaging modality, 2-[F]fluoro-2-deoxy-D-glucose (F-FDG) positron emission tomography can be used to obtain information about ...

journal_title：Nuclear medicine communications

authors： Ak I,Ozalp S,Yalçin OT,Zor E,Vardareli E

更新日期：2004-09-01 00:00:00

abstract：:The British Nuclear Medicine Society has developed a process for the service-specific organizational audit of nuclear medicine departments. This process identified the need for a scheme suitable for the audit of the scientific and technical standards of a department providing such a service. This document has evolved ...

journal_title：Nuclear medicine communications

authors： Jarritt PH,Perkins AC,Woods SD,British Nuclear Medicine Society.

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:99mTc-depreotide (NeoTect) is a synthetic somatostatin analogue, which binds to somatostatin receptor (SSTR) subtypes 2, 3 and 5. Imaging patients with non-Hodgkin's lymphoma (NHL) using the somatostatin analogue In-pentetreotide (Octreoscan) has demonstrated the feasibility of identifying lymphoma sites wit...

journal_title：Nuclear medicine communications

authors： Bushnell DL,Menda Y,Madsen MT,Link BK,Kahn D,Truhlar SM,Juweid M,Shannon M,Murguia JS

更新日期：2004-08-01 00:00:00

abstract：:Positron emission tomography (PET) is increasingly used clinically to provide functional information on disease processes, especially in oncology using the glucose analogue 2-[18F]fluoro-2-deoxy-D-glucose (F-FDG). In the clinical setting it has become standard practice to use simplified imaging protocols compared to t...

journal_title：Nuclear medicine communications

authors： Hallett WA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Positron emission tomography (PET) imaging using [18F]fluorodeoxyglucose (18F-FDG) is recognized to have a major role in oncological imaging. Over recent years there has been a steady increase in the use of gamma camera PET (GCPET) systems as these are less expensive than dedicated PET scanners and facilitat...

journal_title：Nuclear medicine communications

authors： Marshall C,Mustafa S,Wheatley DC,Eremin JE,El-Sheemy M,Jibril JA,Eremin O,Griffiths PA

更新日期：2004-07-01 00:00:00

abstract：AIM:To test the applicability of Tc-dextran joint scintigraphy in the assessment of disease activity in patients with rheumatoid arthritis (RA), and to compare it with the clinical disease activity scores and laboratory parameters. METHODS:Twenty-seven patients with RA were investigated using Tc-dextran joint scintigr...

journal_title：Nuclear medicine communications

authors： Kaya M,Tuna H,Fatih Firat M,Tuna F,Seren G,Necmi Yigitbasi O

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The new anti-cancer drug imatinib mesylate inhibits the tyrosine kinase growth factor receptor, c-KIT, and has shown spectacular activity in patients with gastrointestinal stromal tumours (GISTs). OBJECTIVE:To assess whether fluorodeoxyglucose positron emission tomography (FDG PET) is suitable for response ...

journal_title：Nuclear medicine communications

authors： Jager PL,Gietema JA,van der Graaf WT

更新日期：2004-05-01 00:00:00

abstract：INTRODUCTION:It has been suggested that renal retention function can be estimated by differentiation of the Patlak-Rutland plot. AIM:To evaluate the error resulting from this method. METHODS:A total of 5800 renograms were generated by convolving real input functions with artificial retention functions. Ten bi-exponen...

journal_title：Nuclear medicine communications

authors： Kuyvenhoven JD,Ham HR,Piepsz A

更新日期：2004-05-01 00:00:00

abstract：:An increased uptake of bone-seeking radiopharmaceuticals into malignant bone lesions could further improve the diagnostic accuracy of routine bone scanning. The tracers used in clinical routine for bone scanning are methylene-diphosphonate (MDP), dicarboxypropane-diphosphonate (DPD) and ethylenediaminetetramethylene-p...

journal_title：Nuclear medicine communications

authors： Fueger BJ,Mitterhauser M,Wadsak W,Ofluoglu S,Traub T,Karanikas G,Dudczak R,Pirich C

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the success rate in lymphatic mapping and sentinel node biopsy in breast cancer using two radiopharmaceuticals. METHODS:The study included 119 breast cancer patients who underwent lymphoscintigraphy after a single intratumoral injection of 99mTc-labelled human albumin co...

journal_title：Nuclear medicine communications

authors： Leidenius MH,Leppänen EA,Krogerus LA,Smitten KA

更新日期：2004-03-01 00:00:00

abstract：:Cerebral blood flow (CBF) can be quantified non-invasively using the brain perfusion index (BPI) determined from radionuclide angiographic data generated with 99mTc-hexamethylpropylene amine oxime (99mTc-HMPAO). When measuring the BPI, manual drawing of regions of interest (ROIs) (manual ROI method) for the extraction...

journal_title：Nuclear medicine communications

authors： Murase K,Nagayoshi M,Uenishi Y,Kawamata M,Yamazaki Y,Takasawa M,Oku N,Hatazawa J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:123I has been promoted for diagnostic imaging as a means of avoiding 'stunning'. It has also been suggested that the more favourable physical characteristics and consequent enhanced imaging resolution provided by 123I offers a more accurate diagnostic assessment of the extent of disease prior to therapy. Thi...

journal_title：Nuclear medicine communications

authors： Cohen JB,Kalinyak JE,McDougall IR

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:Respiratory gated perfusion single photon emission computed tomography (SPECT) was applied to reduce respiratory lung motion effects and to reliably assess perfusion impairment in various lung diseases. METHODS:After injection of 259 MBq of 99mTc macroaggretated albumin (99mTc-MAA), gating was performed using ...

journal_title：Nuclear medicine communications

authors： Suga K,Kawakami Y,Zaki M,Yamashita T,Matsumoto T,Matsunaga N

更新日期：2004-02-01 00:00:00

abstract：:To clarify the biological significance of [18F]fluorodeoxyglucose (18F-FDG) accumulation in patients with cancer, we assessed the relationships between 18F-FDG uptake and glucose transporter-1 (GLUT-1) expression and proliferation rate in human glioma and lung cancer. We obtained FDG PET images and measured standardiz...

journal_title：Nuclear medicine communications

authors： Chung JK,Lee YJ,Kim SK,Jeong JM,Lee DS,Lee MC

更新日期：2004-01-01 00:00:00

abstract：:Many materials and types of implant have been used to achieve a cosmetic effect and prosthesis motility in the anophthalmic socket. Hydroxyapatite remains the implant material of choice for producing the most natural prosthesis motility while porous polyethylene shows promising characteristics as another useful materi...

journal_title：Nuclear medicine communications

authors： Pan MH,Wu YW,Yen RF,Tzen KY,Liao SL,Kao CH

更新日期：2003-12-01 00:00:00

abstract：:The aim of this study was to compare the extent and severity of wall motion abnormalities, perfusion and glucose metabolism, in recent myocardial infarction in patients with and without revascularization. Forty-nine patients were studied (82% men; mean age 58 years) by using echocardiography, 201Tl single photon emiss...

journal_title：Nuclear medicine communications

authors： González P,Massardo T,Coll C,Redondo F,Yovanovich J,Jofré J,Chamorro H,Humeres P,Sierralta P,Ramírez A,Kunstmann S,López H,Aramburú I,Brugère S

更新日期：2003-11-01 00:00:00

abstract：:The assessment and appropriate clinical management of patients with acute chest pain and non-diagnostic electrocardiograms remain a continuing clinical problem. Accordingly, there is considerable interest in evaluating new strategies to improve early diagnostic accuracy in patients with possible acute myocardial ischa...

journal_title：Nuclear medicine communications

authors： Anand DV,Lahiri A

更新日期：2003-10-01 00:00:00

abstract：:Optical luciferase gene imaging is emerging as a method to monitor gene expression in small animals. However, there is concern over how regional availability of exogenously administered substrate may affect photon emission. We thus synthesized [125I]iodo-D-luciferin, which demonstrated substrate characteristics for fi...

journal_title：Nuclear medicine communications

authors： Lee KH,Byun SS,Paik JY,Lee SY,Song SH,Choe YS,Kim BT

更新日期：2003-09-01 00:00:00

abstract：:The combination of a diagnosis of malignancy and hospitalization, isolation and radioactivity of a radionuclide therapy may have an important effect on the psychological equilibrium of patients and may hamper compliance and acceptability. We performed a psychiatric evaluation in order to study psycho-pathological mani...

journal_title：Nuclear medicine communications

authors： Brans B,van den Eynde F,Audenaert K,Vervaet M,van Daele K,van Heeringen C,Dierckx RA

更新日期：2003-08-01 00:00:00

abstract：:We have devised an original predictive residual index (PRI) using 99mTc diethylenetriaminepentaacetic acid galactosyl human serum albumin (99mTc-GSA) liver dynamic SPET for the pre-operative assessment of hepatectomy, including the prediction of residual liver function before hepatectomy. The aim of this study was to ...

journal_title：Nuclear medicine communications

authors： Nishiyama Y,Yamamoto Y,Hino I,Satoh K,Wakabayashi H,Ohkawa M

更新日期：2003-07-01 00:00:00

abstract：:Lymphoscintigraphy for sentinel node (SN) detection has been studied extensively in melanoma and breast cancer. In head and neck squamous cell carcinoma (HNSCC), however, experience in this field is relatively meagre. The purpose of this study was to document and evaluate lymphoscintigraphic findings in HNSCC patients...

journal_title：Nuclear medicine communications

authors： Nieuwenhuis EJ,Pijpers R,Castelijns JA,Snow GB

更新日期：2003-06-01 00:00:00

abstract：:Lymphocele is a common cause of fluid collection in post-renal transplant patients. Most of these patients are routinely followed up with 99mTc diethylenetriaminepentaacetate renal dynamic scintigraphy. The present study retrospectively reviews the range of findings with renal dynamic scintigraphy in documented lympho...

journal_title：Nuclear medicine communications

authors： Kumar R,Bharathi Dasan J,Choudhury S,Guleria S,Padhy AK,Malhotra A

更新日期：2003-05-01 00:00:00

abstract：:A method for attenuation and scatter correction of brain single photon emission computed tomography (SPECT) is described where computed tomography (CT) images of the brain are used for the calculation of attenuation maps. The method is evaluated for the substance 99mTc hexamethylpropylene amine oxime. A transmission d...

journal_title：Nuclear medicine communications

authors： Larsson A,Johansson L,Sundström T,Ahlström KR

更新日期：2003-04-01 00:00:00

abstract：:Mammography is the screening test of choice for breast cancer. Its low specificity leads to a large number of unnecessary biopsies. Scintimammography, with either Tc-sestamibi (MIBI) or Tc-anti-carcinoembryonic antigen (CEA) Fab', has been proposed as a non-invasive test to lower the high false positive rate of mammog...

journal_title：Nuclear medicine communications

authors： Sanidas EE,Koukouraki S,Velidaki A,Manios A,Stathopoulos E,De Bree E,Kafousi M,Kodogiannis E,Karkavitsas N,Tsiftsis DD

更新日期：2003-03-01 00:00:00

abstract：:Our aim was to determine whether the Ca2+ ion or cell membrane Ca2+ and Na+/Ca2+ ion transport systems are involved in maintaining the cell-associated activity of technetium-99m-hexakis-methoxy-isobutyl-isonitrile (99mTc-MIBI) and technetium-99m-ethylene-bis[bis(2-ethoxyethyl)phosphin] (99mTc-tetrofosmin) in tumour ce...

journal_title：Nuclear medicine communications

authors： Arbab AS,Ueki J,Koizumi K,Araki T

更新日期：2003-02-01 00:00:00

abstract：:It is generally accepted that the quality of myocardial images deteriorates with increasing patient weight. This is attributed to a reduction of counts detected from the myocardium. In this paper we have looked at the count reduction in obese patients and suggest a workable algorithm to increase the injected activity ...

journal_title：Nuclear medicine communications

authors： Notghi A,Williams N,Smith N,Goyle S,Harding LK

更新日期：2003-01-01 00:00:00

abstract：:The aim of this study was to demonstrate that radionuclide sentinel node detection can be applied to patients with non-palpable breast cancer. One hundred and ten consecutive women with unilateral breast cancer were studied. Group 1 was made up of 80 patients with palpable breast cancer (mean age, 58 years) and group ...

journal_title：Nuclear medicine communications

authors： Fernandez A,Escobedo A,Benito E,Azpeitia D,Guma A,Prieto L,Moreno A,Martin-Comin J

更新日期：2002-12-01 00:00:00

abstract：:Planar pulmonary scintigraphy is still regularly performed for the evaluation of pulmonary embolism (PE). However, only about 50-80% of cases can be resolved by this approach. This study evaluates the ability of tomographic acquisition (single photon emission computed tomography, SPECT) of the perfusion scan to improv...

journal_title：Nuclear medicine communications

authors： Collart JP,Roelants V,Vanpee D,Lacrosse M,Trigaux JP,Delaunois L,Gillet JB,De Coster P,Vander Borght T

更新日期：2002-11-01 00:00:00